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ADFC8MD Dissolution System of Sampling and Collection
ADFC8MD Dissolution System of Sampling and Collection

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Accurately and automatically complete dissolution and sampling process.

ADFC8MD Dissolution system of sampling and collection is consists of RCZ-8M Dissolution Tester, RZQ-8D Sampling and Collection System. Accurately and automatically complete dissolution and sampling process.

Features

1     Dissolution Tester provided with 8 vessels and 8 shafts.

2     Automatically positioning shafts with vessels in coaxiality, easy to handle and use.

3     Ventral plane at headstock as the whole vessel cover to reduce medium evaporation.

4     Simultaneous drug drop fitting for paddle method.

5     Separate design for sapling system and collection system.

6     Sampling and Collection System adopt precise injector as sampling drive.

7     Using 8 channels of valve with high precision and high chemical stability.

8     Anti-absorption of polytetrafluoroethylene tubing with high chemical stability.

9     Adopting filter Infiltration technology before the experiment to reduce absorption.

10   The cross-contamination is avoided because of adopting circulation technique of return liquid to before sampling and pipe emptying technology after sampling.

11    It has equal liquid supplement function.

12    With 8 channels separate piping systems to meet a comparison requirement between the blank and the standard in the dissolution testing.

13    Sampling with two-stage filtration, using10 μm diameter of cylindrical filter head in the initial filtering, not filter or 0.8 μm / 0.45 μm/ 0. 2μm aperture of φ25 mm injection type filter can be chosen according to actual needs in the second filtering.

14    Test tube rack of 15 lines, for up to 120 test tubes.

15    Sealed silicon rubber cap for test tube to avoid sample evaporation and contamination.

16    Big screen LCD display, easy operation.

17    Clean solution is replaceable during tubing clean.

18    Power-on password, Easy to manage instrument.

19    Dissolution sample collection system consistent with domestic and international pharmacopoeia of drug dissolution and sampling requirements.

 

Specification

1     Rotating speed: 25-250 rpm.±1%

2     Temperature control: 5°C(room temperature) to 45°C.±0.3°C

3     Number of sampling channels: 8

4     Max. sampling times: 15

5     Max. sampling interval: 99 hours 59 minutes

6     Min. sampling interval: 1 minute for the first one; 4 to 6 minutes for others

                          (according to sampling volume and solution supplement )

7     Continuous operating duration: 99 hours 59 minutes x 15

8     Sampling filtration time: ≤ 30 seconds

9     Sampling volume (or amount of adding volume): 1 ml to 10 ml

10   Sampling accuracy: ± 2%  When sampling volume is 5ml, each channel average

11   Filtering aperture: 10µm polyethylene filter at first filtering

                     Φ25mm injection cellulose filter at second filtering

Diameter up to 0.22µm

12    Sampling point position: midpoint between top of basket (or paddle) and liquid surface, 10mm distance from inner wall of the vessel

13   Reserved communication Interface , communicating with the PC through cable or LAN

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