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Alpha Lipoic acid
Alpha Lipoic acid

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1,Superior Quality of ALA
2,CAS NO.:1077-28-7
3,Molecular formula: C8H14O2S2

Lipoic acid 

IUPAC name

(R)-5-(1,2-dithiolan-3-yl)pentanoic acid

Other names

α-lipoic acid (alpha lipoic acid), thioctic acid, 6,8-dithiooctanoic acid

Identifiers 

CAS number

1200-22-2 

PubChem

6112

ChemSpider

5886 

MeSH

Lipoic+acid

SMILES

O=C(O)CCCC[C@H]1SSCC1

InChI

InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1 
Key: AGBQKNBQESQNJD-SSDOTTSWSA-N 

InChI=1/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
Key: AGBQKNBQESQNJD-SSDOTTSWBZ

Properties 

Molecular formula

C8H14O2S2

Molar mass

206.33 g/mol

Appearance

yellow needle-like crystals

Solubility inwater

soluble in ethanol, sodium salt is soluble in water

Pharmacology 

Bioavailability

30% (oral)

Related compounds 

Related compounds

Lipoamide
Asparagusic acid


Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

CAS number

1200-22-2 

PubChem

6112

ChemSpider

5886 

MeSH

Lipoic+acid

SMILES

O=C(O)CCCC[C@H]1SSCC1

InChI

InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1 
Key: AGBQKNBQESQNJD-SSDOTTSWSA-N 

InChI=1/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
Key: AGBQKNBQESQNJD-SSDOTTSWBZ

Properties 

Molecular formula

C8H14O2S2

Molar mass

206.33 g/mol

Appearance

yellow needle-like crystals

Solubility inwater

soluble in ethanol, sodium salt is soluble in water

Pharmacology 

Bioavailability

30% (oral)

Related compounds 

Related compounds

Lipoamide
Asparagusic acid

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

CAS NO.:1077-28-7

Molecular formula:  C8H14O2S2 

Function:Alpha lipoic acid is a fatty acid found naturally inside every cell in the body. It’s needed by the body to produce the energy for our body’s normal functions. Alpha lipoic acid converts glucose(blood sugar) into energy. Alpha lipoic acid is also an antioxidant, a substance that neutralizes potentially harmful chemicals called free radicals. What makes alpha lipoic acid unique is that it functions in water and fat. It appears to be able to recycle antioxidants such as vitamin C and glutathione after they have been used up. Alpha lipoic acid increases the formation of glutathione.

Specification:

Appearance:

Yellow Crystal Fine Powder

Identification:

Meets the requirements

Melting point(B.P):

60-62 degree C

Solubility(1N NaOH):

Clear and Pale Yellow

Residue on Ignition:

0.1% Max.

Heavy Metals:

10ppm Max.

 Pb:

2ppm Max.

 Cd:

2ppm Max.

 Hg:

2ppm Max.

 As:

2ppm Max.

Chloride:

0.1% Max.

Loss on Drying:

0.2% Max.

Assay(by SUP Method):

99.0-101.0%

Specific Optical Rotation:

-1to +1Degree

Related Substanes(by HPLC)

 

6,8-Epitrithiotic Acid :

0.1% Max.

Single impurities:

0.1% Max.

Total impurities:

0.5% Max.

Polymers(by TLC):

2.0% Max.

Residue Solvents(by GC) 

 

Toluene:

30ppm Max.

Ethyl acetate:

250ppm Max.

Cyclohexane:

0.20%Max.

Microbiology:

 

Total Aerobic Count:

1000CFU/gMax.

Yeast &Mold:

<100CFU/g Max.

Salmonella:

Negative

E.Coil:

Negative

 

 

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