Low shearing force, rapid solution circulation , shorter mixing time, and ability of linear scale up.

 

Shanghai RITAI introduces a new generation of microcarrier Cell Culture Bioreactors. We adopt centrifugal lifting type Agitator, which has features of low shearing force, rapid solution circulation , shorter mixing time, and ability of linear scale up. And we adopt new type of aeration tube, which has features of foam free deep aeration, oxygen Transfer Rate (Kla between 4-8) satisfy.. Moreover, we also adopt unique decanting column, which has features of Simple structure, stable and reliable, Perfusion rate higher than 5 times of the working volume/per day, a self cleaning function and of features of liquid level being automatically controlledApplicationModelCELLIPOWER08 SYSTEMWorking volume5L,10L,15LFilling volume65-80%MaterialSpecial type of magnetic silicone glass , which can resist temp. and pressure.
Wetted parts are SS316L, and others is SS304.Stainless steel part finishinside surface is 0.28-0.6μm by mechanical polishing, ( passivation or electropolish are optional)
outside surface is 0.4-0.8μm by satin finish.PressureATM (atmospheric pressure)Agitation11. Fermentor use servo motor
2.top mechanical agitator , single mechanical seal
3.speed range:50-200rpm
4. Centrifugal lifting type agitatorEquips of vessel1.using alcohol flame inoculation
2.electrical heater
3.PH,DO, temp. sensor foam and level probe port, etc.constructionbench-top
One fermentor vessel with one control system (simens PLC and HMI)Operating panelChinese and English versionMain components and controls of systemPH1.On-line check and measure, and digitization fully automatic control;
2.PH, CO2 and base gang control. Mass flow meter automatically adjusting CO2, peristaltic pump automatically adjusting base.
3.Control range 2-12pH, measure precision±0.01 pH, control precision±0.1 pH;
4. It has auto alarm function.
5.pH sensor and signal transmission line, mettler ToledoDO1.On-line check and measure; digital display.
2.Range 0-200%, precision ±1%;
3.It has auto alarm function;
4.DO sensor and signal transmission line, mettler ToledoFeed controlperfusion1.Automatically control and automatically alarm;
2.peristaltic pump automatically feeding and perfusionTemp. control1.PID fully digitization signal processing, digitization control settings
2.Measure range 0-150°C, control range 15-45°C,control precision±0.2°C
3.Pt 100Ωtemp. Sensor
4.system with electrical heater to control the temp inside vesselRotate speed1.Automatically control , with auto alarm function
2.servo frequency converter to adjust the speed.Air flowAutomatically adjusting with massflow metersterilizationShould sent to autoclave for sterilizationControlSiemens PLC, and Siemens 10.4” LCD touch screen(HMI) and RITAI programPC1.PC with kingview software for recording function (optional)
2.PC with simens remote control and kingview recording function (optional)
3.printer (optional)