To aminomethylbenzoic acid tranexamic acid derivatives, is a kind of antifibrinolytic drugs to stop bleeding, hemostasis and aminocaproic acid, tranexamic acid, but the effect is stronger, strength is 7 ~ 2 amino acid 10 times, aminomethylbenzoic acid, and similar in toxicity.
The chemical structure of tranexamic acid and lysine, competitive inhibition of plasminogen to fibrin adsorption, to prevent their activation, protect the fiber protein was not degraded by the enzyme and dissolved, ultimately achieve hemostasis effect. All applicable in the treatment of acute or chronic, localized or systemic primary fibrinolysis hyperfunction caused by bleeding, such as obstetric hemorrhage, renal hemorrhage, hypertrophy of the prostate, hemophilia hemorrhage, pulmonary tuberculosis hemoptysis, bleeding in the stomach, liver, lung, spleen and other viscera bleeding after operation; can also be used when abnormal operation bleeding.
The clinical effect of tranexamic acid on insect bites, eczema and dermatitis, simple purpura, chronic urticaria, artificial sex urticaria, rash and drug poisoning effect, also have certain effects on erythroderma, scleroderma, SLE, erythema multiforme, herpes zoster and alopecia areata, curative effect of hereditary angioedema is also good. Treatment of melasma general medicine bear fruit about 3 weeks, 5 weeks of D treatment markedly effective, 60. Each oral 0.25 ~ 0.5g, 3 ~ 4 times a day. Can be side effects of nausea, fatigue, pruritus, abdominal discomfort, and diarrhea in a few patients, symptoms disappeared after stopping drug.