Avanafil (Steroids) Assay: 99% min. CAS: 330784-47-9 Molecular Formula:C23H26ClN7O3 Molecular Weight:483.9506 Molecular Structure: Character: White to Off-White Cyrstalline Solid. Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Categories: Active Pharmaceutical Ingredients; Cnbio; Erectile Dysfunction; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; API\'s. Avanafil is an oral drug that is used for treating impotence (the inability to attain or maintain a penile erection), also known as erectile dysfunction (ED). It is in a class of drugs called phosphodiesterase inhibitors that also includes tadalafil (Cialis), sildenafil (Viagra) and vardenafil (Levitra). Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis, and, at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis. Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the penis. The nitric oxide causes an enzyme, guanylate cyclase, to produce cyclic guanosine monophosphate (cGMP). It is cGMP that is primarily responsible for increasing and decreasing the size of blood vessels carrying blood to and from the penis, respectively, and causing an erection. When the cGMP is destroyed by another enzyme, Mobile Phone No.:+86-18872220718 TEL:+86-27-50756029 FAX:+86-27-88048077 E-mail:[email protected] Skype ID:live:judy10010