1,CAS #:481-74-3
2,Molecular formula:C15H10O4
3,Molecular weight:254.24
4,Formulation:golden yellow powder
5,Purity:99%

Product  Description

1. Name: Chrysophanol ;

2. Alias: Chrysophanic acid, 3-methylchrysazin ;

3. Chemical name: 9, 10-Anthracenedione, 1, 8-dihydroxy-3-methyl-;

4. Chemical formula: C15H10O4 ;

5. Molecular weight: 254.23 ;

6. Appearance: Orange slice ;

7. CAS NO:481-74-3;

8. Physical properties: six square or slanted shaped crystalline (ethanol or benzene), melting point is 196 °, sublimation. Almost insoluble in water and slightly soluble in cold alcohol, easily soluble in boiling ethanol, soluble in benzene, chloroform, ether, acetone, glacial acetic acid and very slightly soluble in petroleum ether. , Melting point is 198 °. IRνKBrmac cm -1:1680,1630,1607;UVλMeOHmac,nm(logε):224(4.73),257(4.48),277(4.18),287(4.18),429(4.14);MS m/e(%):254(100).

9. Pharmacological action: with more obvious effects of treating cough. Against Streptococcus, pneumococcal, influenza strains and Neoformans ,and it has varying degrees  restraint. It can promote the gut of the animal, and can cause neural excitation and muscle paralysis. Oral or subcutaneous injection, has significantly reduced the role of blood clotting time.

10. uses:  be used for antibactering .

Rhaponticin and chrysophanol 8-o-β-D-glucopyranoside isolated from the rhizomes of Rheum undulatum (Family Polygonaceae) are metabolized to rhapontigenin and chrysophanol, respectively, by human intestinal microflora. Most intestinal bacterial isolated from human feces catalyzed these metabolic pathways. Among rhaponticin and chrysophanol 8-o-β-D-glucopyranoside and their metabolites, rhapontigenin had the most potent inhibitory activity on a hyaluronidase, a histamine release from mast cell and passive coutaneous anaphylaxis (PCA) PCA reaction. The inhibitory activity of rhapontigenin was more potent than that of disodium cromoglycate, one of the commercial anti-allergic drugs. These results suggest that rhaponticin in the rhizomes of R. undulatum is a prodrug that has an extensitve anti-allergic property.