... prothrombinase II, VII, IX, X. The shortage of vitamin k1 can caused disorder or abnormal synthesis of prothrombinase. Clinically, there ... cramps3.In recent years, reports said that High-dose vitamin K1 can promote liver cell viability, enhanced monocyte-macrophage phagocytosis, ... used in clinical bleeding caused by a lack of vitamin k1, Such as bleeding caused by obstructive jaundice, biliary fistula, ...