... effects.7 However, diarrhea, skin rash, headache, and fatigue may be experienced in less than 20% of people, according to other ... with methylsulfonylmethane. Some researchers have suggested that the resulting MSM could be responsible for the benefits attributed to DMSO. If so, MSM ... addition, as a natural substance found in food, MSM would be expected to have a good safety profile. SUGGESTED USE: Some ...