... fails because of other severe acne, cystic acne, acne conglobata.[Dose and usage]Oral: Initially, the daily 0.5mg/kg, 1 ... several times a day. After 4 weeks, the daily maintenance dose of 0.1mg ~ 1mg/kg, usually 16 weeks for treatment ... , chapped and other mucous membranes. 2, liver and kidney dysfunction, high blood lipids and the disabled who are allergic to the ...