... combine the prothrombinase II, VII, IX, X. The shortage of vitamin k1 can caused disorder or abnormal synthesis of prothrombinase. Clinically ... cramps.3.In recent years, reports said that High-dose vitamin K1 can promote liver cell viability, enhanced monocyte-macrophage ... and sodium salicylate; Hemorrhage of newborn and shortage of vitamin k1 caused by long-term use of broad-spectrum antibiotics ...