... around joints that is associated with osteoarthritis. Glucosamine HCL contains 98% glucosamine, whereas Glucosamine Sulfate contains 75% glucosamine. Glucosamine HCL and GlucosamineSulfate behave similarly in the gastrointestinal environment ... high blood pressure, on salt orpotassium restricted diets or those having adverse reactions to sulfate. Glucosamine is chiefly used in medicine. It has ...